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Name: how does tirzepatide work vs semaglutide vs. Tirzepatide: Which GLP-1 Works Better Tirzepatide vs. Semaglutide: Key Differences
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Slow or absent weight loss may indicate insufficient dosing, medication absorption issues, or unaddressed metabolic barriers

Extended exclusivity carries similar downsides: a JAMA Health Forum analysis of four top-selling drugs found delayed generic entry led to approximately $3.5 billion in excess spending over two years

[Related Content] In a large real-world study of more than 125,000 adults published in JAMA Network Open , nearly two-thirds of patients using GLP-1s specifically for weight loss discontinued treatment within the first year